Bluefin Tuna Carpaccio
$21.00castelvetrano olives, lemon & pistachio
Mano a Mano
Chicago, IL
2534 N Milwaukee Ave, Chicago, IL, 60647-263075 itemsUpdated March 28, 2026
Structured menu data
Antipasti
Focaccia di Recco
$18.00THIN & crispy stuffed with stracchino cheese
Fried Mozzarela
$5.00Mozzarela from Puglia
Meatball Napoletana
$16.00grass-fed beef, parmesan, pomodoro. 4pc/order
Mozz & Arancini
$18.00basil & tomato jam
Tiny Fried Calamari
$22.00calabrese oregano, sea salt, diavola sauce
Bianco
2023 Arneis
$85.00Marcarini, Roero DOCG, Piedmont
2023 Grillo
$60.00Feudo Maccari, Sicily
2024 Erbaluce
$75.00Cantina Bianchi, 'Luminae', Piedmont
2024 Garganega
$70.00Pieropan, Soave
2024 Pinot Grigio
$45.00Benvolio, Veneto
2024 Verdicchio
$55.00Sartarelli, le Marche
2024 Vermentino
$65.00Surrau, Sardinia
Coffee Culture
Affogato
$12.00Americano
$5.00Espresso
$4.00Espresso Tonic
$14.00Dessert
Apple Crisp
$12.00spiced apple & amaretti
Classic Tiramisu
$14.00Mascarpone, Marsala & Cocoa
Gelato alla Minuto - chocolate & hazelnut
$14.00Gelato alla Minuto - fior di latte, chocolate & cherries
$14.00Featured Cocktails
Espresso Martini
$18.00Giardiniera Martini
$18.00Mano Manhattan
$18.00Mirto Margarita
$17.00Pathfinder Daiquiri
$14.00Pathfinder, Lemon, Fee Foam
Pistachio Martini
$18.00Legendary Wines & Seasonal Favorites
2009 Gaja 'Sori Tildin'
$600.00Nebbiolo, Barbaresco DOCG
2009 Ornellaia
$550.00Cabernet Sauvignon, Toscana IGT
2015 Ca'Del Bosco
$260.00Annamaria Clementi Brut, Chardonnay/Pinot Nero, Franciacorta DOCG
2015 Rocca Delle Macie
$155.00Tenuta Fizzano, Chianti Classico DOCG
2016 Domini Del Leone
$260.00Amarone Della Valpolicella DOCG
2019 Montevertine 'Le Pergole Torte'
$475.00Sangiovese, Toscana IGT
2020 Travaglini 'Tre Vigne'
$175.00Nebbiolo, Gattinara DOCG, Piedmont
2022 G. Mascarello 'Toetto'
$200.00Freisa, Langhe DOC
2022 Gaja 'Idda'
$185.00Carricante, Etna Bianco DOC
NV Andre Heucq Assemblage
$180.00Champagne AOC
Negroni Service
Amaro
$15.00Bianco
$15.00Classic Gin - Hendricks
$15.00La Luna Mezcal
$15.00Phony Negroni
$14.00Tiramisu Negroni
$15.00Pasta
Aglio e Olio
$18.00garlic, chili flakes & parmesan. Gluten Free Available
Alla Gricia
$24.00Bucatini, Guanciale, Pecorino Romano, black pepper, red onion, olive oil. Gluten Free Available
Amatriciana
$24.00Rigatoni, pomodoro, pecorino, red onions & guanciale. Gluten Free Available
Cacio e Pepe
$23.00Roman classic. Toasted pepper, pecorino & parmesan. Gluten Free Available
Carbonara
$27.00crisp guanciale, & golden egg yolk. Gluten Free Available
Cavatelli
$22.00basil pesto genovese topped w/ parmesan reggiano & toasted pinenuts. Gluten Free Available
Limone
$16.00Amalfi Coast classic. Spaghetti, lemon, heavy cream & parmesan. Gluten Free Available
Pappardelle
$24.00oyster mushrooms, bacon & parmesan. Gluten Free Available
Pomodoro & Meatballs
$24.00a familiar classic: parmesan & basil. Gluten Free Available
Ravioletti
$25.00beef short rib, robiola & lemon
Ravioli
$29.00lobster brodo, basil & lemon
Spicy Lamb Sugo
$26.00Rigatoni, lamb sausage, jimmy nardello peppers & pecorino. Gluten Free Available
Stuffed Farfalle
$27.00butternut squash, brown butter, walnut & sage
Tagliatelle
$29.00Traditional ragu alla bolognese. Gluten Free Available
Rosato
2022 Groppello
$65.00Cataldo Calabretta, Calabria
2024 Barbera
$60.00Picco Maccario, Piedmont
Rosso
2014 Corvina
$85.00Villa Loren, Amarone della Valpolicella DOCG
2016 Negaroamaro
$65.00Copertino, Pulgia
2017 Barbera
$55.00Mario Giribaldi, Alba, Piedmont
2019 Nebbiolo
$95.00Ca'Nova, 'Bocciolo', Ghemme DOCG, Alto Piedmont
2020 Montepulciano
$75.00Tenuta Rio Maggio, Marche
2022 Sangiovese
$60.00Bodega San Gregorio, 'Il Palio', Chianti, Toscana
2024 Gaglioppo
$45.00Fattoria San Francesco, Calabria
Spumante
NV Lambrusco
$60.00Carafoli, Lambrusco, Emilia-Romagna
NV Prosecco
$55.00Il Cucciolo, Glera, Veneto
NV Rosato
$75.00Cirelli, Montepulciano, Abruzzo
Tuscan Roast
Barolo Braised Beef
$28.00parmesan risotto
Garlic Chicken
$28.00white beans, lemon & balsamela
Verdure
Arugula caesar
$16.00parmesan reggiano & spicy ciabatta breadcrumbs
Eggplant Parmigiana
$18.00diavola sauce & burrata
Very Verde insalata
$16.00greens, herbs, pistachios & chili flakes
Zucchini Flowers
$15.00fior di latte mozzarella, pecorino cheese, and ricotta cheese, rolled in peperoncino flakes, lightly breaded. 3pc/order